Website of Dr. Joseph George



Published abstracts


1. Joseph George, and Mikihiro Tsutsumi: Epigallocatechin gallate treatment decreases osteopontin expression and attenuates N-Nitrosodimethylamine induced hepatic fibrosis in rats.

Hepatology 60 Suppl S1 (2014) 583A.

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2. Nobuyuki Toshikuni, Kazuaki Ozaki, Joseph George, Mikihiro Tsutsumi, and Tomiyasu Arisawa: Serum endocan as a novel prognostic biomarker in hepatocellular carcinoma patients.

United European Gastroenterology Journal 1 Suppl 1 (2013) A-453.
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3. Joseph George, Nobuhiko Hayashi, Masayoshi Takeuchi, Tomiyasu Arisawa, and Mikihiro Tsutsumi. Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease.

Gastroenterology 144 Suppl 1 (2013) S-912.
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4. Joseph George, Mutsumi Tsuchishima, Nobuyuki Toshikuni, Takashi Saito, and Mikihiro Tsutsumi. Ethanol and ageing promote pathogenesis of hepatocellular carcinoma in mice.

Proc. American Association for Cancer Research 54 (2013) 3584.

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5. Mikihiro Tsutsumi, Joseph George, Tomoe Nomura, Nobuhiko Hayashi, and Tomiyasu Arisawa. Serum osteopontin levels as a diagnostic marker for hepatic fibrosis.

Alcoholism: Clinical and Experimental Research 36 Suppl S2 (2012) 59A.

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6. Mutsumi Tsuchishima, Joseph George, Hisakazu Siroeda, Takashi Saito, Tomiyasu Arisawa and Mikihiro Tsutsumi. Mechanism of the pathogenesis of hepatocellular carcinoma during chronic administration of ethanol in mice.

Hepatology 54 Suppl S1 (2011) 1300A.

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7. Joseph George, Jeanine DfArmiento and Mikihiro Tsutsumi. Human MMP-1 transgene protects experimentally induced hepatic fibrosis in mice.

Hepatology 54 Suppl S1 (2011) 1223A.

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8. Joseph George, Mikihiro Tsutsumi and Jeanine DfArmiento.Human MMP-1 transgene protects experimentally induced hepatic fibrosis in mice.

Hepatology International 5 (2011) 296-297.

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9. Joseph George, M. Isabel Fiel and Natalia Nieto. Carbon tetrachloride-induced liver injury and fibrosis correlates with osteopontin expression in mice.

Hepatology 52 Suppl S1 (2010) 453A.

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10. Aritz Lopategi, Joseph George and Natalia Nieto. Hepatic stellate cells secretes osteopontin under oxidative stress and contributes to fibrogenic response mediated through integrin ƒżvƒÀ3 and PI3K/pAkt pathway.

Hepatology 52 Suppl S1 (2010) 1260A-1261A.

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11. Elena Arriazu, Tung Ming Leung, Suzanna Paganos, Joseph George, M. Isabel Fiel and Natalia Nieto. SPP1 contributes to non-alcoholic steatohepatitis in mice fed a methionine-choline deficient diet.

Hepatology 52 Suppl S1 (2010) 1053A.

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12. Joseph George, Mikihiro Tsutsumi and Jeanine DfArmiento. MMP-13 deletion attenuates N-nitrosodimethylamine induced hepatic fibrosis in mice.

Hepatology 52 Suppl S1 (2010) 1284A.

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13. Joseph George, Naren L. Banik and Swapan K. Ray. Knockdown of connective tissue growth factor and treatment with temozolomide inhibited invasion, angiogenesis, and tumorigenesis of human glioblastomas.

Proc. American Association for Cancer Research 51 (2010) 681.

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14. Joseph George, Naren L. Banik and Swapan K. Ray. Combination of 4-HPR and EGCG induces apoptosis and inhibits angiogenesis and tumorigenesis of neuroblastoma SH-SY5Y and SK-N-DZ cells.

Proc. American Association for Cancer Research 51 (2010) 578.

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15. Joseph George, Mikihiro Tsutusmi and Jeanine DfArmiento. MMP-13 deletion protects monocrotaline induced liver injury in mice.

Hepatology 50 Suppl 4 (2009) 823A-824A.

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16. Joseph George, Naren L. Banik and Swapan K. Ray. Survivin knockdown enhanced efficacy of N-(4-hydroxyphenyl) retinamide for apoptosis in human glioblastoma U138MG and U251MG cells and inhibited invasion, angiogenesis, and tumor growth.

Proc. American Association for Cancer Research 50 (2009) 4662.

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17. Joseph George, Naren L. Banik and Swapan K. Ray. Combination of 4-HPR and Genistein increases apoptosis in glioblastoma cells and inhibits invasion, angiogenesis, and tumor growth.

Journal of Neurochemistry 108 Suppl 1 (2009) 92-93.

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18. Joseph George and Mikihiro Tsutusmi. Interfering of connective tissue growth factor mRNA protects N-nitrosodimethylamine induced toxic liver injury in rats.

Hepatology 48 Suppl 1 (2008) 912A.

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19. Joseph George and Mikihiro Tsutusmi. Elevated serum ƒÀ-glucuronidase reflects hepatic lysosomal fragility following toxic liver injury in rats.

Hepatology 48 Suppl 1 (2008) 929A.

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20.

Joseph George, Stephen Tomlinson, Naren L. Banik and Swapan K. Ray. Synergistic effect of Bcl-xL small interfering RNA and genistein in human neuroblastoma SH-SY5Y and SK-N-DZ cells for induction of apoptosis and inhibition of angiogenesis and tumor growth in nude mice.

Proc. American Association for Cancer Research 49 (2008) 4406.

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21.

Joseph George, Naren L. Banik and Swapan K. Ray. siRNA mediated knockdown of Bcl-2 and low-dose taxol treatment in human glioblastoma U251MG cells induces apoptosis, inhibits cell invasion, angiogenesis, and tumor growth in nude mice.

Proc. American Association for Cancer Research 49 (2008) 4389.

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22.

Joseph George, James S. Norris, Naren L. Banik and Swapan K. Ray. Simultaneous siRNA mediated downregulation of hTERT and treatment with interferon-gamma in human glioblastoma SNB-19 and LN-18 cells causes cell cycle arrest and inhibits invasion, angiogenesis, and tumor growth in nude mice.

Proc. American Association for Cancer Research 49 (2008) 1834.

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23.

Joseph George, Naren L. Banik, Swapan K. Ray. siRNA-mediated knockdown of Bcl-2 in human glioblastoma cell lines increased taxol-mediated apoptosis.

Journal of Neurochemistry 102 Suppl 1 (2007) 259.

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24. Joseph George, Christopher S. Gondi, Meena Gujrati, Dzung H. Dinh and Jasti S. Rao. Restoration of TFPI-2 in a human glioblastoma cell line triggers caspase mediated pathway and apoptosis.

Proc. American Association for Cancer Research 48 (2007) 3661.
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25. Joseph George, Christopher S. Gondi, Meena Gujrati, Dzung H. Dinh, William C. Olivero and Jasti S. Rao. Treatment with a recombinant adeno-associated virus expressing the TFPI-2 gene simultaneously downregulates MMP-9 and VEGF in a human glioblastoma cell line.

Proc. American Association for Cancer Research 47 (2006) 957.

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26.

Joseph George, Kazuki Nemoto, Teruo Miyata and Yoshinori Kuboki: Honeycomb collagen scaffold for the in vitro differentiation of mesenchymal stem cells into osteoblasts.

Tissue Engineering 8 (2002) 1245-1246.

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27.

Kazuki Nemoto, Hiroko Takita, Ryota Yoshimoto, Joseph George, Teruo Miyata and Yoshinori Kuboki: Geometry of honeycomb collagen scaffold gives chamber type microenvironmental units for ectopic osteogenesis when implanted with purified BMP cocktail into rat skin.

Tissue Engineering 8 (2002) 1148-1149.

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28.

Joseph George, Mikihiro Tsutusmi and Shujiro Takase. Expression of TIMP-1 and TIMP-2 in N-nitrosodimethylamine induced hepatic fibrosis in rats.

Hepatology 32 Pt.2 (2000) 505A.

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29.

Joseph George, Mikihiro Tsutsumi, Chen Wunbill, Mutsumi Tsuchishima and Shujiro Takase: Mechanism of the increased serum hyaluronic acid in rats treated with N-nitrosodimethylamine.

Journal of Gastroenterology and Hepatology 15 (2000) F74.

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30.

Joseph George and Gowri Chandrakasan: Collagen metabolism in dimethylnitrosamine induced hepatic fibrosis in rats.

FASEB Journal 11 (1997) A1094.

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31.

Joseph George and Gowri Chandrakasan: Structural and functional alterations in liver during fibrosis.

ICMR Bulletin 26 (1996) 36-37.

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32. Joseph George and Gowri Chandrakasan: Metabolism of liver collagen in dimethylnitrosamine induced hepatic fibrosis.

Immunology and Cell Biology 73 (1995) A14.

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